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1

Intracellular degradation of Helicobacter pylori VacA toxin as a determinant of gastric epithelial cell viability

Foegeding, Nora J., Raghunathan, Krishnan, Campbell, Anne M., Kim, Sun Wook, Lau, Ken S., Kenworthy, Anne K., Cover, Timothy L., Ohi, Melanie D.

Journal:

Infection and Immunity

Year:

2019

Language:

english

File:

PDF, 1.52 MB

english, 2019

2

Yersinia Enterocolitica

Cover, Timothy L., Aber, Robert C.

Journal:

New England Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 1.71 MB

english, 1989

3

In search of the Helicobacter pylori VacA mechanism of action

Emanuele Papini, Mario Zoratti, Timothy L. Cover

Journal:

Year:

2001

Language:

english

File:

PDF, 244 KB

english, 2001

4

Helicobacter pylori adaptation in vivo in response to a high salt diet

Loh, John T., Gaddy, Jennifer A., Algood, Holly M. Scott, Gaudieri, Silvana, Mallal, Simon, Cover, Timothy L.

Journal:

Infection and Immunity

Year:

2015

Language:

english

File:

PDF, 1.53 MB

english, 2015

5

Functional properties of Helicobacter pylori VacA toxin m1 and m2 variants

Caston, Rhonda R., Sierra, Johanna C., Foegeding, Nora J., Truelock, Mandy D., Campbell, Anne M., Frick-Cheng, Arwen E., Bimczok, Diane, Wilson, Keith T., McClain, Mark S., Cover, Timothy L.

Journal:

Infection and Immunity

Year:

2020

File:

PDF, 1.73 MB

2020

6

Release ofHelicobacter pylori vacuolating cytotoxin by both a specific secretion pathway and budding of outer membrane vesicles. Uptake of released toxin and vesicles by gastric epithelium

Fiocca, Roberto, Necchi, Vittorio, Sommi, Patrizia, Ricci, Vittorio, Telford, John, Cover, Timothy L., Solcia, Enrico

Journal:

The Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 519 KB

english, 1999

7

Recovery from lactacidosis-induced glial cell swelling with the aid of exogenous anion channels

Takashi Nabekura, Shigeru Morishima, Timothy L. Cover, Shin-Ichiro Mori, Hiroshi Kannan, Shizuo Komune, Yasunobu Okada

Journal:

Year:

2003

Language:

english

File:

PDF, 551 KB

english, 2003

8

Helicobacter pylori infection in japanese patients with adenocarcinoma of the stomach

Martin J. Blaser, Kensuke Kobayashi, Timothy L. Cover, Ping Cao, Irene D. Feurer, Guillermo I. Pérez-pérez

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 555 KB

english, 1993

9

Analysis of hopQ alleles in East Asian and Western strains of Helicobacter pylori

Ping Cao, Kerry Jo Lee, Martin J. Blaser, Timothy L. Cover

Journal:

FEMS Microbiology Letters

Year:

2005

Language:

english

File:

PDF, 128 KB

english, 2005

10

Acid-induced expression of an LPS-associated gene in Helicobacter pylori

Catherine C. McGowan, Antoaneta Necheva, Stuart A. Thompson, Timothy L. Cover, Martin J. Blaser

Journal:

Molecular Microbiology

Year:

1998

Language:

english

File:

PDF, 2.11 MB

english, 1998

11

Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells

Mark S. McClain, Wayne Schraw, Vittorio Ricci, Patrice Boquet, Timothy L. Cover

Journal:

Molecular Microbiology

Year:

2000

Language:

english

File:

PDF, 295 KB

english, 2000

12

Promoter analysis of Helicobacter pylori genes with enhanced expression at low pH

Catherine C. McGowan, Antoaneta S. Necheva, Mark H. Forsyth, Timothy L. Cover, Martin J. Blaser

Journal:

Molecular Microbiology

Year:

2003

Language:

english

File:

PDF, 637 KB

english, 2003

13

The vacuolating cytotoxin of Helicobacter pylori

Timothy L. Cover

Journal:

Molecular Microbiology

Year:

1996

Language:

english

File:

PDF, 621 KB

english, 1996

14

Host response to Helicobacter pylori infection before initiation of the adaptive immune response

Holly M. Scott Algood, Judith Gallo-Romero, Keith T. Wilson, Richard M. Peek Jr, Timothy L. Cover

Journal:

FEMS Immunology & Medical Microbiology

Year:

2007

Language:

english

File:

PDF, 197 KB

english, 2007

15

Helicobacter pylori and mitogen-activated protein kinases mediate activator protein-1 (AP-1) subcomponent protein expression and DNA-binding activity in gastric epithelial cells

Song-Ze Ding, Igor N. Olekhnovich, Timothy L. Cover, Richard M. Peek Jr, Michael F. Smith Jr, Joanna B. Goldberg

Journal:

FEMS Immunology & Medical Microbiology

Year:

2008

Language:

english

File:

PDF, 647 KB

english, 2008

16

Evaluation of cytotoxic activity in fecal filtrates from patients with Campylobacter jejuni or Campylobacter coli enteritis

Timothy L. Cover, Guillermo I. Perez-Perez, Martin J. Blaser

Journal:

FEMS Microbiology Letters

Year:

1990

Language:

english

File:

PDF, 213 KB

english, 1990

17

Helicobacter pylori HopQ outer membrane protein attenuates bacterial adherence to gastric epithelial cells

John T. Loh, Victor J. Torres, Holly M. Scott Algood, Mark S. McClain, Timothy L. Cover

Journal:

FEMS Microbiology Letters

Year:

2008

Language:

english

File:

PDF, 159 KB

english, 2008

18

Helicobacter pylori VacA, a paradigm for toxin multifunctionality

Cover, Timothy L., Blanke, Steven R.

Journal:

Nature Reviews Microbiology

Year:

2005

Language:

english

File:

PDF, 344 KB

english, 2005

19

Over The Fence

A.W. Harris, Timothy L. Cover, Anthony P. Moran

Journal:

Year:

1997

Language:

english

File:

PDF, 246 KB

english, 1997

20

Non-invasive Genotyping of Helicobacter pylori cagA, vacA, and hopQ from Asymptomatic Children

Liviu A. Sicinschi, Pelayo Correa, Luis E. Bravo, Richard M. Peek Jr, Keith T. Wilson, John T. Loh, Maria C. Yepez, Benjamin D. Gold, Dexter T. Thompson, Timothy L. Cover, Barbara G. Schneider

Journal:

Year:

2012

Language:

english

File:

PDF, 144 KB

english, 2012

21

Soluble Proteins Produced by Probiotic Bacteria Regulate Intestinal Epithelial Cell Survival and Growth

Fang Yan, Hanwei Cao, Timothy L. Cover, Robert Whitehead, M. Kay Washington, D. Brent Polk

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 1.63 MB

english, 2007

22

Genome sequence analysis ofHelicobacter pyloristrains associated with gastric ulceration and gastric cancer

Mark S McClain, Carrie L Shaffer, Dawn A Israel, Richard M Peek, Timothy L Cover

Journal:

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

23

InHelicobacter pyloriauto-inducer-2, but not LuxS/MccAB catalysed reverse transsulphuration, regulates motility through modulation of flagellar gene transcription

Feifei Shen, Laura Hobley, Neil Doherty, John T Loh, Timothy L Cover, R Elizabeth Sockett, Kim R Hardie, John C Atherton

Journal:

BMC Microbiology

Year:

2010

Language:

english

File:

PDF, 1.94 MB

english, 2010

24

Helicobacter pylori Vacuolating Cytotoxin (VacA) Disorganizes the Cytoskeletal Architecture of Gastric Epithelial Cells

Rama Pai, Timothy L. Cover, Andrzej S. Tarnawski

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 406 KB

english, 1999

25

β2 Integrin Mediates Entry of a Bacterial Toxin into T Lymphocytes

Timothy L. Cover

Journal:

Cell Host & Microbe

Year:

2008

Language:

english

File:

PDF, 81 KB

english, 2008

26

High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy

Catherine El-Bez, Marc Adrian, Jacques Dubochet, Timothy L. Cover

Journal:

Journal of Structural Biology

Year:

2005

Language:

english

File:

PDF, 619 KB

english, 2005

27

VacA from Helicobacter pylori: a hexameric chloride channel

Hideki Iwamoto, Daniel M. Czajkowsky, Timothy L. Cover, Gabor Szabo, Zhifeng Shao

Journal:

Year:

1999

Language:

english

File:

PDF, 281 KB

english, 1999

28

Multiple Oligomeric States of the Helicobacter pylori Vacuolating Toxin Demonstrated by Cryo-electron Microscopy

Marc Adrian, Timothy L. Cover, Jacques Dubochet, John E. Heuser

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 1.38 MB

english, 2002

29

Posttranslational changes in band 3 in adult and aging brain following treatment with ergoloid mesylates, comparison to changes observed in Alzheimer's disease

Cathleen C. Cover, Jeff E. Poulin, Monica R. Gustafson, Timothy Wyant, Debra N. Gamble, Marguerite M.B. Kay

Journal:

Year:

1996

Language:

english

File:

PDF, 868 KB

english, 1996

30

An intracellular target for Helicobacter pylori vacuolating toxin

Timothy L Cover

Journal:

Trends in Microbiology

Year:

1998

Language:

english

File:

PDF, 108 KB

english, 1998

31

Helicobacter pylori genotypes, host factors, and gastric mucosal histopathology in peptic ulcer disease

Kyi T Tham, Richard M Peek Jr, John C Atherton, Timothy L Cover, Guillermo I Perez-Perez, Yu Shyr, Martin J Blaser

Journal:

Human Pathology

Year:

2001

Language:

english

File:

PDF, 254 KB

english, 2001

32

Commentary: Helicobacter pylori Transmission, Host Factors, and Bacterial Factors

Timothy L. Cover

Journal:

Gastroenterology

Year:

1997

Language:

english

File:

PDF, 254 KB

english, 1997

33

Helicobacter pylori factors associated with disease

Timothy L. Cover, Martin J. Blaser

Journal:

Gastroenterology

Year:

1999

Language:

english

File:

PDF, 33 KB

english, 1999

34

Characterization of Hela cell vacuoles induced by Helicobacter pylori broth culture supernatant

Timothy L. Cover, Susan A. Halter, Martin J. Blaser

Journal:

Human Pathology

Year:

1992

Language:

english

File:

PDF, 1.96 MB

english, 1992

35

617 Iron Deficiency Amplifies the Pathogenic Potential of Carcinogenic cag+ Helicobacter pylori via Enhancing Function of the cag Type IV Secretion System

Jennifer M. Noto, Jennifer Gaddy, Josephine Y. Lee, M. Blanca Piazuelo, David Friedman, Judith Romero-Gallo, Shumin Tan, Keith T. Wilson, Pelayo Correa, Timothy L. Cover, Manuel R. Amieva, Richard M.

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 74 KB

english, 2012

36

Global analysis of Helicobacter pylori gene expression in human gastric mucosa

James E. Graham, Richard M. Peek Jr*, ‡, Uma Krishna, Timothy L. Cover

Journal:

Gastroenterology

Year:

2002

Language:

english

File:

PDF, 301 KB

english, 2002

37

Epidermal Growth Factor Receptor Activation Protects Gastric Epithelial Cells From Helicobacter pylori-Induced Apoptosis

Fang Yan, Hanwei Cao, Rupesh Chaturvedi, Uma Krishna, Stuart S. Hobbs, Peter J. Dempsey, Richard M. Peek Jr, Timothy L. Cover, M. Kay Washington, Keith T. Wilson, D. Brent Polk

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 2.22 MB

english, 2009

38

Helicobacter pylori in Health and Disease

Timothy L. Cover, Martin J. Blaser

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 1001 KB

english, 2009

39

β-Catenin and p120 Mediate PPARδ-Dependent Proliferation Induced by Helicobacter pylori in Human and Rodent Epithelia

Toni A. Nagy, Lydia E. Wroblewski, Dingzhi Wang, M. Blanca Piazuelo, Alberto Delgado, Judith Romero–Gallo, Jennifer Noto, Dawn A. Israel, Seth R. Ogden, Pelayo Correa, Timothy L. Cover, Richard M. Pee

Journal:

Gastroenterology

Year:

2011

Language:

english

File:

PDF, 4.36 MB

english, 2011

40

Analysis of a β-helical region in the p55 domain ofHelicobacter pylorivacuolating toxin

Susan E Ivie, Mark S McClain, Holly M Scott Algood, D Borden Lacy, Timothy L Cover

Journal:

BMC Microbiology

Year:

2010

Language:

english

File:

PDF, 878 KB

english, 2010

41

Mimicry of a Host Anion Channel by a Helicobacter pylori Pore-Forming Toxin

Czajkowsky, Daniel M., Iwamoto, Hideki, Szabo, Gabor, Cover, Timothy L., Shao, Zhifeng

Journal:

Biophysical Journal

Year:

2005

Language:

english

File:

PDF, 221 KB

english, 2005

42

Structural Analysis of the Oligomeric States of Helicobacter pylori VacA Toxin

Chambers, Melissa G., Pyburn, Tasia M., González-Rivera, Christian, Collier, Scott E., Eli, Ilyas, Yip, Calvin K., Takizawa, Yoshimasa, Lacy, D. Borden, Cover, Timothy L., Ohi, Melanie D.

Journal:

Journal of Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

43

The proton pump inhibitor omeprazole inhibits acid survival of Helicobacter pylori by a urease-independent mechanism

McGowan, Catherine C., Cover, Timothy L., Blaser, Martin J.

Journal:

Gastroenterology

Year:

1994

Language:

english

File:

PDF, 666 KB

english, 1994

44

Sa1864 Iron Deficiency Reveals an Aberrant Morphology Phenotype Exhibited by CagA-Deficient Helicobacter pylori Strains

Noto, Jennifer M., Lee, Josephine Y., Gaddy, Jennifer, Romero-Gallo, Judith, Cover, Timothy L., Amieva, Manuel R., Peek, Richard M.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 151 KB

english, 2013

45

Structural Characterization of the Helicobacter Pylori VacA Toxin by Single Particle Em and X-Ray Crystallography

Chambers, Melissa G., Pyburn, Tasia, González-Rivera, Christian, Collier, Scott E., Takizawa, Yoshimasa, Lacy, D. Borden, Cover, Timothy L., Ohi, Melanie D.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 34 KB

english, 2013

46

Control of gene expression in Helicobacter pylori using the Tet repressor

McClain, Mark S., Duncan, Stacy S., Gaddy, Jennifer A., Cover, Timothy L.

Journal:

Journal of Microbiological Methods

Year:

2013

Language:

english

File:

PDF, 473 KB

english, 2013

47

The M2 Form of the Helicobacter pylori Cytotoxin has Cell Type-Specific Vacuolating Activity

Cristina Pagliaccia, Marina De Bernard, Pietro Lupetti, Xuhuai Ji, Daniela Burroni, Timothy L. Cover, Emanuele Papini, Rino Rappuoli, John L. Telford and Jean-Marc Reyrat

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.51 MB

english, 1998

48

The Vacuolating Toxin from Helicobacter pylori Forms Hexameric Pores in Lipid Bilayers at Low pH

Daniel M. Czajkowsky, Hideki Iwamoto, Timothy L. Cover and Zhifeng Shao

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.91 MB

english, 1999

49

Acid-Induced Dissociation of VacA, the Helicobacter pylori Vacuolating Cytotoxin, Reveals Its Pattern of Assembly

Timothy L. Cover, Phyllis I. Hanson and John E. Heuser

Journal:

The Journal of Cell Biology

Year:

1997

Language:

english

File:

PDF, 3.67 MB

english, 1997

50

Reconstitution of Helicobacter pylori VacA Toxin from Purified Components

González-Rivera, Christian, Gangwer, Kelly A., McClain, Mark S., Eli, Ilyas M., Chambers, Melissa G., Ohi, Melanie D., Lacy, D. Borden, Cover, Timothy L.

Journal:

Year:

2010

Language:

english

File:

PDF, 3.09 MB

english, 2010

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